• Reduce text
  • Restore text size
  • Increase the text
  • Print
Homepage image for the Toulouse INRA center. © Inra, INRA Toulouse

Toulouse

Headlines
Attribute Type Value
ast_remote_id string 380438
ast_tv_id string 1
ast_type_code string 1
ast_type string 'picture'
ast_title string 'Nanoparticules de dioxyde de titane (E171)'
ast_descr string '

Nanoparticules de dioxyde de titane (E171)

'
ast_tags string ''
ast_metavalues string ''
ast_player_id string 0
ast_embed string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-dbfb1-picture_original-nanoparticules-de-dioxyde-de-titane-e171.jpghttps://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-1bed4-picture_photo-nanoparticules-de-dioxyde-de-titane-e171.jpghttps://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-2da4a-picture_photo_fixed_size-nanoparticules-de-dioxyde-de-titane-e171.jpghttps://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-1f57e-picture_custom-nanoparticules-de-dioxyde-de-titane-e171.jpghttps://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-bdb6c-picture_thumbnail-nanoparticules-de-dioxyde-de-titane-e171.jpghttps://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-44c4c-picture_thumbnail_fixed_size-nanoparticules-de-dioxyde-de-titane-e171.jpghttps://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-7e3bb-picture_photo_watermarked-nanoparticules-de-dioxyde-de-titane-e171.jpghttps://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-361ae-picture_photo_watermarked_fixed_size-nanoparticules-de-dioxyde-de-titane-e171.jpghttps://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-613f4-picture_custom_watermarked-nanoparticules-de-dioxyde-de-titane-e171.jpghttps://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-95fe1-picture_thumbnail_watermarked-nanoparticules-de-dioxyde-de-titane-e171.jpghttps://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-db84d-picture_thumbnail_watermarked_fixed_size-nanoparticules-de-dioxyde-de-titane-e171.jpghttps://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-eb976-picture_client_format_0-nanoparticules-de-dioxyde-de-titane-e171.jpghttps://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-40f9d-picture_client_format_1-nanoparticules-de-dioxyde-de-titane-e171.jpghttps://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-6a9cb-picture_client_format_2-nanoparticules-de-dioxyde-de-titane-e171.jpghttps://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-23b3c-picture_client_format_3-nanoparticules-de-dioxyde-de-titane-e171.jpghttps://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-6f599-picture_client_format_4-nanoparticules-de-dioxyde-de-titane-e171.jpghttps://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-a857a-picture_client_format_5-nanoparticules-de-dioxyde-de-titane-e171.jpghttps://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-e33a6-picture_client_link_2-nanoparticules-de-dioxyde-de-titane-e171.jpghttps://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-1c403-picture_client_link_4-nanoparticules-de-dioxyde-de-titane-e171.jpghttps://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-86041-picture_client_link_5-nanoparticules-de-dioxyde-de-titane-e171.jpg'
ast_thumbnail_url string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/media/thumbnail-380438-nanoparticules-de-dioxyde-de-titane-e171.jpg'
ast_capture_date string ''
ast_author string 'Toxalim'
ast_is_active string 1
ast_is_editable string 1
ast_obsolete string 0
tv_key string 'fre'
copyright string 'Inra'
caption string ''
titleEnglish string ''
descrEnglish string 'Titanium dioxide (E171) nanoparticles'
copyrightEnglish string 'INRA'
metavalues array Array(17)
>inra-reference string ''
>inra-commentaire string ''
>inra-centre-de-recherche string ''
>inra-departement-recherche string ''
>inra-unite-recherche string ''
>inra-credit string ''
>inra-couleur-dominante string ''
>inra-orientation string ''
>inra-copyright string 'Inra'
>inra-type-licence string ''
>gsa_index string 'Yes'
>inra-annales-bap string ''
>inra-annales-corps string ''
>inra-annales-annee string ''
>inra-copyright-english string 'INRA'
>inra-description-english string 'Titanium dioxide (E171) nanoparticles'
>inra-title-english string ''
obsolete string 0
img_src array Array(20)
>original string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-dbfb1-picture_original-nanoparticules-de-dioxyde-de-titane-e171.jpg'
>small string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-1bed4-picture_photo-nanoparticules-de-dioxyde-de-titane-e171.jpg'
>large string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-2da4a-picture_photo_fixed_size-nanoparticules-de-dioxyde-de-titane-e171.jpg'
>custom string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-1f57e-picture_custom-nanoparticules-de-dioxyde-de-titane-e171.jpg'
>thumbnail_small string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-bdb6c-picture_thumbnail-nanoparticules-de-dioxyde-de-titane-e171.jpg'
>thumbnail_large string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-44c4c-picture_thumbnail_fixed_size-nanoparticules-de-dioxyde-de-titane-e171.jpg'
>watermarked_small string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-7e3bb-picture_photo_watermarked-nanoparticules-de-dioxyde-de-titane-e171.jpg'
>watermarked_large string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-361ae-picture_photo_watermarked_fixed_size-nanoparticules-de-dioxyde-de-titane-e171.jpg'
>watermarked_custom string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-613f4-picture_custom_watermarked-nanoparticules-de-dioxyde-de-titane-e171.jpg'
>watermarked_thumbnail_small string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-95fe1-picture_thumbnail_watermarked-nanoparticules-de-dioxyde-de-titane-e171.jpg'
>watermarked_thumbnail_large string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-db84d-picture_thumbnail_watermarked_fixed_size-nanoparticules-de-dioxyde-de-titane-e171.jpg'
>image_ratio_1_5_grand string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-eb976-picture_client_format_0-nanoparticules-de-dioxyde-de-titane-e171.jpg'
>image_ratio_1_5_petit string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-40f9d-picture_client_format_1-nanoparticules-de-dioxyde-de-titane-e171.jpg'
>image_ratio_1_57_grand string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-6a9cb-picture_client_format_2-nanoparticules-de-dioxyde-de-titane-e171.jpg'
>image_ratio_1_57_petit string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-23b3c-picture_client_format_3-nanoparticules-de-dioxyde-de-titane-e171.jpg'
>image_ratio_0_71_grand string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-6f599-picture_client_format_4-nanoparticules-de-dioxyde-de-titane-e171.jpg'
>image_ratio_0_71_petit string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-a857a-picture_client_format_5-nanoparticules-de-dioxyde-de-titane-e171.jpg'
>image_link_carroussel string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-e33a6-picture_client_link_2-nanoparticules-de-dioxyde-de-titane-e171.jpg'
>image_link_carre string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-1c403-picture_client_link_4-nanoparticules-de-dioxyde-de-titane-e171.jpg'
>image_link_annuaire string 'https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/380438-86041-picture_client_link_5-nanoparticules-de-dioxyde-de-titane-e171.jpg'
file_url boolean false
ref string '1_380438_1'
Titanium dioxide (E171) nanoparticles. © INRA, Toxalim

Researchers from INRA and their partners1 have studied the effects of oral exposure to titanium dioxide, an additive (E171) commonly used in foodstuffs, especially confectionary. They have shown for the first time that E171 crosses the intestinal barrier in animals and reaches other parts of the body. Immune system disorders linked to the absorption of the nanoscale fraction of E171 particles were observed. The researchers also showed that chronic oral exposure to the additive spontaneously induced preneoplastic lesions in the colon, a non-malignant stage of carcinogenesis, in 40% of exposed animals. Moreover, E171 was found to accelerate the development of lesions previously induced for experimental purposes. While the findings show that the additive plays a role in initiating and promoting the early stages of colorectal carcinogenesis, they cannot be extrapolated to humans or more advanced stages of the disease. The findings were published in the 20 January 2017 issue of Scientific Reports.

News

Units of the Research Centre